Translational Nanobioscience
Our lab is focused on characterizing the interactions of biomacromolecules and nanomaterials with biological systems, and translating scientific insights into engineered solutions to address outstanding needs in medicine, biotechnology, and agriculture. Key research areas include biosensor development, interfacial science, and biophysics. We also develop pharmaceutical drugs and nanomedicines for infectious disease, cancer, and immunology applications, especially lipid nanoparticle technologies. Current projects include:
1. Lipid Nanoparticle Technology for Pharmaceutical Drug and Vaccine Delivery 2. Label-Free Biosensors for Medicine and Biotechnology
3. Peptide and Protein Engineering
4. Lipid Membrane Biotechnology
5. Antimicrobial Lipids: Biophysical Mechanisms and Biological Activities
6. STEM Education and Innovation
학력
Ph.D. in Materials Science and Engineering, Nanyang Technological University (2015) B.S. in Chemistry (summa cum laude), University of Florida (2010)
(2026)
Distinct Membrane-Permeabilizing Interactions of an Antiviral Alkyl Glucoside Detergent: Comparison with Triton X-100 and SDS.
COLLOIDS AND SURFACES B-BIOINTERFACES.
263,
(2026)
Hybrid lipid bilayer platform with restricted flip-flop for probing surfactant-induced membrane disruption: towards biofouling-resistant membranes.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS.
N.A,
N.A
(2025)
Synergistic Membrane Disruption of E. coli Tethered Lipid Bilayers by Antimicrobial Lipid Mixtures.
BIOMIMETICS.
10,
11
(2025)
Curvature-Sensing Peptides for Virus and Extracellular Vesicle Applications.
ACS NANO.
19,
42
(2025)
Mechanobiologically Engineered Mimicry of Extracellular Vesicles for Improved Systemic Biodistribution and Anti-Inflammatory Treatment Efficacy in Rheumatoid Arthritis.
ADVANCED HEALTHCARE MATERIALS.
14,
25
(2025)
Headgroup-driven binding selectivity of alkylphospholipids to anionic lipid bilayers.
COLLOIDS AND SURFACES B-BIOINTERFACES.
255,
N.A.
(2025)
Mitigation Strategies for African Swine Fever Virus Biosecurity: From Virus Inactivation to Pig Health.
TRANSBOUNDARY AND EMERGING DISEASES.
2025,
1
(2025)
Medium-chain fatty acids and monoglycerides: Nanoarchitectonics-based insights into molecular self-assembly, membrane interactions, and applications.
ADVANCES IN COLLOID AND INTERFACE SCIENCE.
340,
N.A
(2025)
Adsorption and Spreading of Sponge-Phase Lipid Nanoparticles on SiO2 and TiO2 Surfaces: Ion-Specific Effects and Particle Structure.
LANGMUIR.
41,
6
(2025)
Manufacturing high-performance flexible sensors via advanced patterning techniques.
INTERNATIONAL JOURNAL OF EXTREME MANUFACTURING.
7,
3
(2025)
Nanopot plasmonic sensor platform for broad spectrum virus detection.
CHEMICAL ENGINEERING JOURNAL.
505,
N.A
(2025)
Unraveling Cholesterol-Dependent Interactions of Alkylphospholipids with Supported Lipid Bilayers.
LANGMUIR.
41,
3
(2024)
Development of a water-dispersible antimicrobial lipid mixture to inhibit African swine fever virus and other enveloped viruses.
VIRUS RESEARCH.
351,
(2024)
Antiviral screening of natural, anti-inflammatory compound library against African swine fever virus.
VIROLOGY JOURNAL.
21,
1
(2024)
Unraveling the Biophysical Mechanisms of How Antiviral Detergents Disrupt Supported Lipid Membranes: Toward Replacing Triton X-100.
LANGMUIR.
40,
12
(2024)
Interindividual- and blood-correlated sweat phenylalanine multimodal analytical biochips for tracking exercise metabolism.
NATURE COMMUNICATIONS.
15,
1
(2023)
Interfacial approach to fabricate covalently and noncovalently attached inverse-phosphocholine supported lipid bilayers on TiO2 and SiO2 surfaces.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY.
128,
-
단행본
(2023)
Quartz Crystal Microbalance-Dissipation Technique for Tracking Dynamic Biomacromolecular Interactions.
Springer Nature.
단독
수상/공훈
ACS Nano Junior Fellow, 2017 American Liver Foundation Herman Lopata Memorial Hepatitis Postdoctoral Research Fellowship Award, 2016 – 2017 Nanyang Technological University MSE Doctorate Technopreneur Award, 2016 Nano Korea Grand Prize Award, 2013 Nanyang President’s Graduate Scholar, 2011 – 2015 Harvard-MIT HST Division Martinos Scholar, 2011 National Science Foundation Graduate Research Fellowship, 2010 Harvard-MIT HST Division MEMP Graduate Fellowship, 2010 University of Florida Department of Chemistry Crow Award, 2010 National Science Foundation CPIMA SURE Fellowship, 2009 Phi Beta Kappa, 2008 UF-HHMI Science for Life Extramural Research Award, 2008 Arnold and Mabel Beckman Foundation Beckman Scholars Fellowship, 2007 University of Florida John V. Lombardi Scholarship, 2006 U.S. Department of Education Robert C. Byrd Honors Scholarship, 2006
